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The slogan is "Prevent The Preventable" so does that mean a new laboratory disease is about to be let loose?


October 2016

Barbara "BJ" Andrews, Editor-In-Chief, SAAB


Canine infectious respiratory disease is not common but that doesn’t matter, it now has its own acronym – CIRD. Does that mean that canine adenovirus type 2 (CAV-2), canine parainfluenza, (CPiV) and disease caused by Bordetella bronchiseptica (Bb) is going to become so common that it needs its own acronym-abbreviation?  Perhaps. See the veterinary marketing release below but first, a little background information.


The first flu vaccine was introduced in 1938, the year I was born, but I don’t recall any “flu” when I was growing up. My children did not receive any flu vaccines and they only had typical colds. Perhaps we were living on some other planet because I don’t recall the Spanish Flu vaccine of 1955 either but says there was a vaccine for it. Thankfully, there was polio vaccine but childhood diseases back then were measles, mumps, and chicken pox which we all caught and developed life-long immunity.


By the 60s we knew about “dog shots” when previous to that, hunting dogs got rabies shots but not much more. Somehow, they didn’t “catch” distemper and those other doggy diseases we are all paranoid about. Well, if you are old enough, you get the point.


If you are of the more gullible generation you will say “things have changed” and will smugly point out that there is more disease now. Yes. That IS my point.  So, doing my duty as editor of I will provide you with a 2005 example of medication marketing which we titled appropriately Prescribing DeathThat expose' was so powerful that the Health Ranger used it to produce a 6 minute VIDEO with the same title.  Read the following information presented exactly as it was circulated to the veterinary community.  Then take time to visit the world's first Vaccine Information Section where our Veterinary consultants first told dog owners about Vaccine Induced Disease (VID) and hope that dog owners will make a wise decision.


Introducing Vanguard® Rapid Resp Intranasal

This family of single-nostril (0.5 mL) respiratory vaccines helps protect dogs from key pathogens associated with Canine Infectious Respiratory Disease (CIRD) and can make administration fast and comfortable.



For vaccination of healthy dogs 8 weeks of age or older as an aid in preventing respiratory disease caused by canine adenovirus type 2 (CAV-2), canine parainfluenza caused by canine parainfluenza virus (CPiV) and disease caused by Bordetella bronchiseptica (Bb).


3 antigenic combinations:

• Bb + CPiV + CAV-2

• Bb + CPiV

• Bb only


Canine Infectious Respiratory Disease (CIRD)

Infectious respiratory disease in dogs can be caused by many different pathogens, both bacterial and viral. In most instances, the clinical signs will be identical regardless of the infecting pathogen.  Because co-infections frequently occur and may lead to more severe symptoms, a multivalent immunization protocol can help PREVENT THE PREVENTABLE.



Efficacy and Safety Studies

Efficacy Study7

Compared to controls:

• Reduced duration of Bordetella bronchiseptica nasal shedding (p<0.0001)

• Reduced cough post-challenge


Safety Study8

No adverse events were reported in the immediate post-vaccination period.

Abnormal health events or reactions reported in the late phase post-vaccination period. (See table on the right)

1-Year Duration of Immunity9

VANGUARD® Rapid Resp Intranasal vaccines have the 1st approved 1-year duration of immunity claim for the Bordetella bronchiseptica fraction.

Study results:

Duration of coughing reduced 84.4% in vaccinates as compared to controls (p<0.0001)

• Strong antibody response post-challenge (days 370 to 398)

• Other respiratory clinical signs reduced


Prime Boost

The use of intranasal and parenteral vaccines may help provide the best Bordetella bronchiseptica protection.10

• When the immune system is exposed to antigens from different routes, a faster and more robust immune response may be achieved

• Mucosal administration followed by systemic vaccination can help to avoid immune exclusion, specifically in seropositive patients11


BRONCHICINE® CAe – The Booster Shot™

• Monovalent

• Parenteral

• Non-infectious12

• Non-adjuvanted


All trademarks are the property of Zoetis Inc., its affiliates and/or its licensors. ©2016 Zoetis Inc. All rights reserved. February 2016. SAB-00290 EST 2002 © 1610


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